Bromide

Bromide

SCHEMBL6680136

Br.CCCCc1nccc2ccccc12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.43
HTR1B known ✓ P28222 1/20 0.38
CYP2A6 P11509 1/20 0.47
F12 P00748 1/20 0.43
PLAU P00749 1/20 0.43
NCF1 P14598 1/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
BACE1 P56817 1/20 0.43
TDP1 Q9NUW8 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 2/20 0.41
PDE10A Q9Y233 1/20 0.39
ABCB11 O95342 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
SCN1A P35498 1/20 0.39
SCN2A Q99250 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31125170 0.98 CYP2A6 (0.48) CYP2A6ACHEF12PLAUNCF1
SCHEMBL4067893 0.98 CYP2A6 (0.48) CYP2A6ACHEF12PLAUNCF1
Iodide SCHEMBL2453300 0.97 CYP2A6 (0.47) CYP2A6ACHEF12PLAUNCF1
Hydrochloric Acid SCHEMBL26126612 0.97 CYP2A6 (0.47) CYP2A6ACHEF12PLAUNCF1
Bromide SCHEMBL3726900 0.95 CYP2A6 (0.46) CYP2A6ACHEF12PLAUNCF1
Bromide SCHEMBL25259916 0.93 CYP2A6 (0.44) CYP2A6ACHEF12PLAUNCF1
Bromide SCHEMBL17317381 0.93 CYP2A6 (0.44) CYP2A6ACHEF12PLAUNCF1
Bromide SCHEMBL3363614 0.93 CYP2A6 (0.44) CYP2A6ACHEF12PLAUNCF1
Bromide SCHEMBL3363045 0.93 CYP2A6 (0.44) CYP2A6ACHEF12PLAUNCF1
Bromide SCHEMBL25252655 0.93 CYP2A6 (0.44) CYP2A6ACHEF12PLAUNCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457838-A1 Method to reduce precipitation in developers for lithographic printing plates Fuji Photo Film B.V. (NL) 2004-09-15 EP disclosed
EP-1455234-A1 Method to reduce precipitation in developers for lithographic printing plates Fuji Photo Film B.V. (NL) 2004-09-08 EP disclosed
US-5580704-A CONTAINING BASIC DYE, ORGANIC SOLVENT HAVING LOW WATER SOLUBILITY, HYDROTROPE AGENT, ANIONIC SURFACTANT; HIGH DYE DENSITY, LOW FOAMABILITY, NONPRECIPITATING, NONSTAINING FUJI PHOTO FILM CO., LTD. (JP) 1996-12-03 US disclosed
EP-0652489-A1 Process for processing a photosensitive lithographic printing plate requiring no fountain solution FUJI PHOTO FILM CO., LTD. (JP) 1995-05-10 EP disclosed