Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 8/20 | 0.52 |
| ▸ | CA2 | P00918 | 8/20 | 0.52 |
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182100 | 0.94 | MEN1 (0.65) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL14630990 | 0.89 | MEN1 (0.71) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL8634131 | 0.88 | MEN1 (0.56) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL19142371 | 0.88 | MEN1 (0.57) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL8632713 | 0.88 | MEN1 (0.57) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL9493064 | 0.88 | MEN1 (0.56) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL9327481 | 0.87 | MEN1 (0.73) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL8631405 | 0.86 | TDP1 (0.58) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL9321356 | 0.86 | TDP1 (0.58) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL12755039 | 0.86 | MEN1 (0.58) | MEN1KMT2AGAATDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133281-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | CIDARA THERAPEUTICS, INC. (US) | 2022-06-23 | — | — | WO | disclosed |