SCHEMBL9493064

SCHEMBL9493064

CCOC(=O)C(CCCCNC(=O)OC(C)(C)C)C(=O)OCC

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
GAA P10253 1/20 0.56
TDP1 Q9NUW8 7/20 0.55
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA12 O43570 5/20 0.50
CA9 Q16790 5/20 0.50
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
ATM Q13315 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 3/20 0.42
POLB P06746 2/20 0.42
MAPT P10636 4/20 0.41
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321356 0.98 TDP1 (0.58) MEN1KMT2AGAATDP1CA1
SCHEMBL8631405 0.98 TDP1 (0.58) MEN1KMT2AGAATDP1CA1
SCHEMBL4474428 0.95 MEN1 (0.62) MEN1KMT2AGAATDP1CA1
SCHEMBL27184888 0.93 MEN1 (0.52) MEN1KMT2AGAATDP1CA1
SCHEMBL6534839 0.93 MEN1 (0.59) MEN1KMT2AGAATDP1CA1
SCHEMBL4478961 0.90 MEN1 (0.68) MEN1KMT2AGAATDP1CA1
SCHEMBL18760388 0.89 MEN1 (0.53) MEN1KMT2AGAATDP1CA1
SCHEMBL24533591 0.88 MEN1 (0.59) MEN1KMT2AGAATDP1CA1
SCHEMBL22961926 0.85 MEN1 (0.54) MEN1KMT2AGAATDP1CA1
Hydrochloric Acid SCHEMBL9416400 0.84 MEN1 (0.52) MEN1KMT2AGAATDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4914226-A Malonic acid derivatives and methods for their synthesis ENIRICERCHE S.P.A. (IT) 1990-04-03 US claimed
EP-0254080-A2 Malonic acid derivatives and methods for their synthesis ENIRICERCHE S.p.A. (IT) 1988-01-27 EP claimed
US-12337036-B2 Compounds and methods for trans-membrane delivery of molecules APOSENSE LTD (IL) 2025-06-24 US disclosed
US-20250027130-A1 Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-23 US disclosed
WO-2023164676-A1 METHODS TO GENERATE NOVEL ACYL-TRNA SPECIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-31 WO disclosed
US-20210052736-A1 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES APOSENSE LTD (IL) 2021-02-25 US disclosed
US-20210052736-A1 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES APOSENSE LTD (IL) 2021-02-25 US disclosed
EP-3735276-A1 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES Aposense Ltd. (IL) 2020-11-11 EP disclosed
EP-0254080-B1 MALONIC ACID DERIVATIVES AND METHODS FOR THEIR SYNTHESIS ENIRICERCHE S.p.A. (IT) 1993-03-17 EP disclosed
EP-0253190-B1 PARTIALLY RETRO-INVERTED TUFTSIN ANALOGUES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ENIRICERCHE S.p.A. (IT) 1992-12-30 EP disclosed
US-4914226-A Malonic acid derivatives and methods for their synthesis ENIRICERCHE S.P.A. (IT) 1990-04-03 US disclosed
US-4816560-A STORAGE STABILITY ENIRICERCHE S.P.A. (IT) 1989-03-28 US disclosed
EP-0254080-A2 Malonic acid derivatives and methods for their synthesis ENIRICERCHE S.p.A. (IT) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12337036-B2 Compounds and methods for trans-membrane delivery of molecules LDLR, NPC1L1, ABCB4 MEN1 1858/4885KMT2A 2787/4885GAA 359/4885
US-20210052736-A1 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES LDLR, NPC1L1, ABCB4 MEN1 1858/4885KMT2A 2787/4885GAA 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.