Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547243 | 0.85 | MAPT (0.62) | MAPTKMT2ATDP1CA1CA2 | |
| SCHEMBL11828207 | 0.85 | CA1 (0.71) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6517455 | 0.83 | LMNA (0.55) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL27616936 | 0.83 | CA12 (0.46) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL27603935 | 0.83 | HSD17B2 (0.69) | MAPTKMT2ACA1CA2CA12 | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.82 | MAPT (0.86) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL21383063 | 0.82 | CA1 (0.57) | MAPTKMT2ATDP1CA1CA2 | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.82 | MAPT (0.86) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL15342989 | 0.82 | PLK1 (0.53) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL6517172 | 0.81 | LMNA (0.53) | MAPTKMT2ACA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081285-A1 | UREA-CONTAINING ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2018-05-03 | — | — | WO | disclosed |
| US-9790213-B2 | Imidazoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN-LA ROCHE INC. (US) | 2017-10-17 | — | — | US | disclosed |
| EP-1577350-B1 | Method for production of halogen-containing phthalocyanine compound | NIPPON CATALYTIC CHEM IND (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-7473777-B2 | Method for production of halogen-containing phthalocyanine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2009-01-06 | — | — | US | disclosed |
| CN-1680380-A | Method for production of halogen-containing phthalocyanine compound | NIPPON CATALYTIC CHEM IND (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-1577350-A1 | Method for production of halogen-containing phthalocyanine compound | Nippon Shokubai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20050203293-A1 | Method for production of halogen-containing phthalocyanine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-09-15 | — | — | US | disclosed |
| EP-0523959-B1 | Novel phthalocyanine compounds, production method thereof, and near infrared ray absorption materials containing the same | NIPPON CATALYTIC CHEM IND (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5359056-A | Lightfastness, solvent solubility | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0523959-A2 | Novel phthalocyanine compounds, production method thereof, and near infrared ray absorption materials containing the same | NIPPON SHOKUBAI CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |