SCHEMBL2453409

SCHEMBL2453409

CCCC(C)(C)C(CC(=O)OCC(C)(C)C)C(=O)OCC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 2/20 0.31
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31
ADRA1A P35348 1/20 0.31
RAB9A P51151 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1244583 0.83 GAA (0.43) LMNAHSD17B10TSHRCYP3A4TDP1
SCHEMBL5275425 0.80 MIF (0.31)
SCHEMBL2456542 0.79 TSHR (0.34) LMNAHSD17B10TSHRCYP3A4NFKB1
SCHEMBL2453413 0.76
SCHEMBL28224625 0.73 CYP4F2 (0.37) HSD17B10TSHRCYP3A4TDP1
SCHEMBL14629675 0.73 HTT (0.41) LMNAHSD17B10
SCHEMBL28311970 0.72 CYP4F2 (0.39) HSD17B10TSHRCYP3A4TDP1
SCHEMBL28472890 0.72 CA2 (0.36)
SCHEMBL6863975 0.71 CA2 (0.44) TSHRCYP3A4TDP1
SCHEMBL28261390 0.71 CYP4F2 (0.41) LMNATSHRCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209125-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-27 US disclosed
EP-3559113-B1 MASTERBATCH COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2024-06-12 EP disclosed
EP-4323415-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2024-02-21 EP disclosed
EP-3765566-B1 POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE BASELL POLIOLEFINE ITALIA SRL (IT) 2023-12-06 EP disclosed
US-11807744-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2023-11-07 US disclosed
WO-2022218869-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-10-20 WO disclosed
US-11339280-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-05-24 US disclosed
US-11319431-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-05-03 US disclosed
US-11306198-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-04-19 US disclosed
EP-3810661-B1 POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE BASELL POLIOLEFINE ITALIA SRL (IT) 2022-02-16 EP disclosed
US-7005487-B2 Catalyst system for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-02-28 US disclosed
EP-1539838-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-06-15 EP disclosed
EP-1525231-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-04-27 EP disclosed
US-20050032633-A1 Propylene polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-02-10 US disclosed
US-20050014631-A1 Catalyst system for the polymerization of olefins BASELL POLYOLEFINE ITALIA S.P.A. (IT) 2005-01-20 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed
WO-2004024785-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-03-25 WO disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed
EP-1088009-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-04-04 EP disclosed
WO-2000063261-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-26 WO disclosed