Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 10/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RPS6KA2 | Q15349 | 5/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 5/20 | 0.32 |
| ▸ | LCP2 | Q13094 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25100167 | 0.89 | POLB (0.38) | POLB | |
| SCHEMBL22484671 | 0.77 | DPP4 (0.33) | MAP4K1RPS6KA2PRKD2LCP2 | |
| SCHEMBL22485042 | 0.77 | DPP4 (0.33) | MAP4K1RPS6KA2PRKD2LCP2 | |
| SCHEMBL21152439 | 0.74 | MAP3K5 (0.36) | POLB | |
| SCHEMBL22484670 | 0.74 | MAP3K5 (0.36) | POLB | |
| SCHEMBL21693807 | 0.69 | MAP4K1 (0.51) | MAP4K1RPS6KA2PRKD2LCP2 | |
| SCHEMBL21706101 | 0.69 | MAP4K1 (0.51) | MAP4K1RPS6KA2PRKD2LCP2 | |
| SCHEMBL22484754 | 0.67 | POLB (0.41) | POLB | |
| SCHEMBL23118868 | 0.66 | — | — | |
| SCHEMBL23118842 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132686-A1 | FUSED BICYCLIC PYRAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |