Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535776 | 1.00 | KDM4E (0.34) | KDM4ELMNACYP2C19NPSR1TSHR | |
| SCHEMBL24535771 | 1.00 | KDM4E (0.34) | KDM4ELMNACYP2C19NPSR1TSHR | |
| SCHEMBL24535919 | 0.82 | IRAK4 (0.31) | — | |
| SCHEMBL8945803 | 0.76 | POLB (0.32) | KDM4ELMNACYP2C19MMP9 | |
| SCHEMBL6124706 | 0.76 | CYP19A1 (0.36) | KDM4ELMNACYP2C19NPSR1TSHR | |
| SCHEMBL7408970 | 0.71 | — | — | |
| SCHEMBL12059262 | 0.71 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL14378011 | 0.70 | TSHR (0.39) | KDM4ELMNACYP2C19NPSR1TSHR | |
| SCHEMBL21645421 | 0.69 | POLB (0.31) | — | |
| SCHEMBL21645418 | 0.69 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132686-A1 | FUSED BICYCLIC PYRAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |