Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535919 | 0.76 | IRAK4 (0.31) | — | |
| SCHEMBL24535771 | 0.76 | KDM4E (0.34) | MMP9KDM4ELMNACYP2C19 | |
| SCHEMBL24535772 | 0.76 | KDM4E (0.34) | MMP9KDM4ELMNACYP2C19 | |
| SCHEMBL24535776 | 0.76 | KDM4E (0.34) | MMP9KDM4ELMNACYP2C19 | |
| SCHEMBL6130820 | 0.73 | MMP9 (0.31) | MMP9ALDH1A1 | |
| SCHEMBL19814031 | 0.72 | — | — | |
| SCHEMBL4909784 | 0.72 | ITGB3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL11365594 | 0.71 | MMP9 (0.30) | MMP9 | |
| SCHEMBL10676973 | 0.70 | KDM4E (0.39) | MMP9ALDH1A1KDM4ELMNACYP2C19 | |
| SCHEMBL7408970 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8053404-A | — | — | None | — | — | JP | disclosed |
| JP-H0853404-A | NEW INTERMEDIATE FOR 4,4-DIALKYL-2-AZETIDINONES | E R SQUIBB & SONS INC | 1996-02-27 | — | — | JP | disclosed |
| CN-1018824-B | Process for preparing 4, 4-dialkyl-2-azetidinones | SQUIBB & SONS INC (US) | 1992-10-28 | — | — | CN | disclosed |
| CN-1014894-B | Process for preparing 4, 4-dialkyl-2-azetidinones | SQUIBB & SONS INC (US) | 1991-11-27 | — | — | CN | disclosed |
| US-4812564-A | Process for preparing 4,4-dialkyl-2-azetidinones utilizing a pyridine (or substituted pyridine) sulfur trioxide complex | E. R. SQUIBB & SONS, INC. (US) | 1989-03-14 | — | — | US | disclosed |