Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535766 | 1.00 | ALOX5 (0.30) | ALOX5 | |
| SCHEMBL18943191 | 0.72 | — | — | |
| SCHEMBL16844627 | 0.71 | — | — | |
| SCHEMBL25917779 | 0.71 | — | — | |
| SCHEMBL21241715 | 0.71 | IRAK4 (0.35) | — | |
| SCHEMBL21241285 | 0.67 | BRD4 (0.36) | ALOX5 | |
| SCHEMBL21241478 | 0.67 | BRD4 (0.36) | ALOX5 | |
| SCHEMBL25587688 | 0.67 | — | — | |
| SCHEMBL18943857 | 0.67 | BRD4 (0.36) | ALOX5 | |
| SCHEMBL14894653 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132686-A1 | FUSED BICYCLIC PYRAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |