Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SAT1 | P21673 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 3/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19083201 | 0.89 | SAT1 (0.36) | KCNH2SAT1 | |
| SCHEMBL3316366 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL27323802 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6DPP4GHSR | |
| SCHEMBL3317300 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL26949296 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6DPP4GHSR | |
| SCHEMBL17827393 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6DPP4GHSR | |
| SCHEMBL3316369 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL19768945 | 0.81 | SAT1 (0.36) | SAT1 | |
| SCHEMBL3317295 | 0.80 | ADH1B (0.50) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL3316370 | 0.80 | ADH1B (0.50) | KCNH2CCR2CYP2D6GHSRKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133034-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2022-06-23 | — | — | WO | disclosed |