SCHEMBL2453855

SCHEMBL2453855

Nc1nsnc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18597711 0.78
SCHEMBL9146690 0.75
SCHEMBL18710348 0.67
SCHEMBL24484539 0.65 MAPT (0.41)
SCHEMBL10414868 0.53 NQO1 (0.50)
SCHEMBL12674462 0.48 NQO1 (0.44)
SCHEMBL430129 0.48
SCHEMBL2362493 0.43 KDM4E (0.41)
SCHEMBL1300603 0.43
SCHEMBL175612 0.43 CASP1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
EP-1737417-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-01-03 EP claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
WO-2005074875-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-18 WO claimed
JP-58180477-A None JP disclosed
JP-6135925-A None JP disclosed
JP-6135925-A None JP disclosed
JP-61018775-A None JP disclosed
CN-120987977-B Amine organic compound and organic photovoltaic cell 广州追光科技有限公司 2026-05-15 CN disclosed
EP-3630115-B1 COMPOSITIONS AND METHODS FOR PREPARING AND USING MITOCHONDRIAL UNCOUPLERS UNIV VIRGINIA PATENT FOUNDATION (US) 2025-12-10 EP disclosed
CN-119350370-A Organic compound containing alkoxy substitution and application thereof 广州追光科技有限公司 2025-01-24 CN disclosed
US-20240067650-A1 MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF LUMIPHORE, INC. 2024-02-29 US disclosed
US-4528375-A Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity BRISTOL-MYERS COMPANY (US) 1985-07-09 US disclosed
US-4528378-A Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity BRISTOL-MYERS COMPANY (US) 1985-07-09 US disclosed
US-4528377-A Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity BRISTOL-MYERS COMPANY (US) 1985-07-09 US disclosed
US-4517366-A ETHANEDIIMIDAMIDE, HISTAMINE HYDROGEN RECEPTOR ANTAGONISTS BRISTOL-MYERS COMPANY (US) 1985-05-14 US disclosed
JP-S58180477-A HISTAMINE H2-ACCEPTOR ANTAGONISTIC SUBSTITUTED 3,4-DIAMINO-1,2,5-THIADIAZOLE BRISTOL MYERS CO 1983-10-21 JP disclosed
EP-0040696-A2 Aminothiadiazoles as gastric secretion inhibitors MERCK & CO. INC. (US) 1981-12-02 EP disclosed
EP-0040696-A2 Aminothiadiazoles as gastric secretion inhibitors MERCK & CO. INC. (US) 1981-12-02 EP disclosed
JP-S06118775-A 0001-01-01 JP disclosed