Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832400 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL1832401 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL9909462 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL15075352 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL1287234 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL13021344 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL14604841 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL21418908 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL21418911 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBGAAMAPK1 | |
| SCHEMBL12477732 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127914-A1 | NUCLEOSIDE-THIODIPHOSPHATE-HEPTOSE COMPOUNDS FOR TREATING CONDITIONS ASSOCIATED WITH ALPK1 ACTIVITY | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2022-06-23 | — | — | WO | disclosed |