Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 5/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414057 | 0.84 | HSD11B1 (0.43) | SYKHSD11B1ALOX5APAADAT | |
| SCHEMBL2414355 | 0.80 | MAP4K4 (0.34) | HSD11B1 | |
| SCHEMBL2415136 | 0.75 | HSD11B1 (0.43) | SYKHSD11B1ALOX5APAADAT | |
| SCHEMBL2414294 | 0.75 | CHUK (0.40) | SYKFPR2SCN9AADORA2AADORA1 | |
| SCHEMBL2412722 | 0.74 | HSD11B1 (0.42) | SYKHSD11B1AADAT | |
| SCHEMBL2415629 | 0.74 | HSD11B1 (0.46) | SYKHSD11B1ALOX5APAADAT | |
| SCHEMBL2416932 | 0.72 | MAP4K4 (0.34) | SYKHSD11B1 | |
| SCHEMBL2411052 | 0.71 | BCDIN3D (0.33) | HSD11B1 | |
| SCHEMBL2413074 | 0.71 | CYP1A2 (0.36) | HSD11B1 | |
| SCHEMBL2416453 | 0.70 | HSD11B1 (0.43) | SYKHSD11B1ALOX5APAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | disclosed |