Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24539589 | 0.88 | TLR7 (0.48) | TLR7AGTR1AGTR2TLR8 | |
| SCHEMBL24539698 | 0.88 | TLR7 (0.47) | TLR7AGTR1AGTR2TLR8 | |
| SCHEMBL24539889 | 0.84 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL30824675 | 0.84 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL29136618 | 0.84 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL27197280 | 0.83 | TLR7 (0.54) | TLR7AGTR1AGTR2 | |
| SCHEMBL24539231 | 0.78 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL31581270 | 0.78 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL29382020 | 0.76 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL18645627 | 0.76 | TLR7 (0.69) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022126263-A1 | IMIDAZOTHIENOPYRIDINE COMPOUNDS AND METHODS OF USE | ZYMEWORKS INC. (CA) | 2022-06-23 | — | — | WO | disclosed |