Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27197472 | 0.89 | TLR7 (0.49) | TLR7AGTR2AGTR1 | |
| SCHEMBL27197273 | 0.88 | AGTR1 (0.42) | TLR7AGTR2AGTR1 | |
| SCHEMBL24539652 | 0.83 | TLR7 (0.51) | TLR7AGTR2AGTR1 | |
| SCHEMBL15698675 | 0.72 | TLR7 (0.74) | TLR7 | |
| SCHEMBL27197279 | 0.72 | TLR7 (0.48) | TLR7 | |
| SCHEMBL24539589 | 0.70 | TLR7 (0.48) | TLR7AGTR2AGTR1 | |
| SCHEMBL24539507 | 0.70 | TLR7 (1.00) | TLR7 | |
| SCHEMBL24539698 | 0.70 | TLR7 (0.47) | TLR7AGTR2AGTR1 | |
| SCHEMBL30634402 | 0.70 | AGTR1 (0.52) | TLR7AGTR2AGTR1 | |
| SCHEMBL2894947 | 0.69 | TLR7 (0.46) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124484-A1 | IMIDAZOTHIENOPYRIDINE COMPOUNDS AND METHODS OF USE | ZYMEWORKS BC INC (CA) | 2024-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124484-A1 | IMIDAZOTHIENOPYRIDINE COMPOUNDS AND METHODS OF USE | DHFR, RARS2, DPYD | TLR7 1139/4885AGTR2 694/4885AGTR1 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.