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SCHEMBL24540586

SCHEMBL24540586

O=C(O)CCC[C@H](NC(=O)N[C@@H](CSC[C@H](NC(=O)C(Cc1c2ccccc2cc2ccccc12)NC(=O)[C@H]1CC[C@H](CNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CC1)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 18/20 0.69
▸ GRPR P30550 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27021194 1.00 FOLH1 (0.69) FOLH1GRPR
SCHEMBL27021191 1.00 FOLH1 (0.69) FOLH1GRPR
SCHEMBL27018685 0.97 FOLH1 (0.65) FOLH1GRPR
SCHEMBL27018670 0.97 FOLH1 (0.65) FOLH1GRPR
SCHEMBL27021058 0.91 FOLH1 (0.67) FOLH1GRPR
SCHEMBL27021143 0.91 FOLH1 (0.79) FOLH1
SCHEMBL24540308 0.91 FOLH1 (0.67) FOLH1GRPR
SCHEMBL27021153 0.91 FOLH1 (0.79) FOLH1
SCHEMBL23979242 0.90 FOLH1 (0.84) FOLH1
SCHEMBL27021119 0.90 FOLH1 (0.67) FOLH1GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022126275-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-23 — — WO disclosed
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