SCHEMBL27021058

SCHEMBL27021058

O=C(O)CCC[C@H](NC(=O)N[C@@H](CCCONC(=O)[C@H](Cc1c2ccccc2cc2ccccc12)NC(=O)[C@H]1CC[C@H](CNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CC1)C(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 18/20 0.67
▸ GRPR P30550 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24540308 1.00 FOLH1 (0.67) FOLH1GRPR
SCHEMBL27018657 0.97 FOLH1 (0.63) FOLH1GRPR
SCHEMBL27021031 0.91 FOLH1 (0.69) FOLH1
SCHEMBL24540249 0.91 FOLH1 (0.69) FOLH1
SCHEMBL27021153 0.91 FOLH1 (0.79) FOLH1
SCHEMBL24540586 0.91 FOLH1 (0.69) FOLH1GRPR
SCHEMBL27021194 0.91 FOLH1 (0.69) FOLH1GRPR
SCHEMBL27021191 0.91 FOLH1 (0.69) FOLH1GRPR
SCHEMBL27021143 0.91 FOLH1 (0.79) FOLH1
SCHEMBL27021119 0.90 FOLH1 (0.67) FOLH1GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018110-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN ALPHA-9 ONCOLOGY INC. (CA) 2024-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018110-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN KLK3, FOLH1, TMEM14C FOLH1 2/4885GRPR 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback