Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989024 | 0.89 | TRPM8 (0.53) | TRPM8SERPINE1TRPV1EPHX1LMNA | |
| SCHEMBL2628712 | 0.89 | TRPM8 (0.50) | TRPM8TRPV1EPHX1 | |
| SCHEMBL14664195 | 0.88 | TRPM8 (0.67) | TRPM8TRPV1LMNA | |
| SCHEMBL2628703 | 0.88 | TRPM8 (0.67) | TRPM8TRPV1LMNA | |
| SCHEMBL15131619 | 0.88 | TRPM8 (0.67) | TRPM8TRPV1LMNA | |
| SCHEMBL24540509 | 0.88 | TRPM8 (0.47) | TRPM8SERPINE1TRPV1MAPTCYP4A11 | |
| SCHEMBL24540840 | 0.88 | TRPM8 (0.47) | TRPM8SERPINE1TRPV1MAPTCYP4A11 | |
| SCHEMBL24540473 | 0.86 | TRPM8 (0.49) | TRPM8TRPV1EPHX1 | |
| SCHEMBL2628667 | 0.86 | TRPM8 (0.50) | TRPM8EPHX1 | |
| SCHEMBL2628617 | 0.86 | TRPM8 (0.49) | TRPM8TRPV1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |