Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 5/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112530 | 1.00 | CNR1 (0.37) | CNR1CCR2CETPCYP2C9CYP2C19 | |
| SCHEMBL29112531 | 1.00 | CNR1 (0.37) | CNR1CCR2CETPCYP2C9CYP2C19 | |
| SCHEMBL29681950 | 0.89 | ESR2 (0.36) | CCR2CETPCYP2C9CYP2C19TRPA1 | |
| SCHEMBL29112299 | 0.89 | HSD11B1 (0.34) | CCR2CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL24540302 | 0.89 | HSD11B1 (0.34) | CCR2CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL29681851 | 0.89 | HSD11B1 (0.34) | CCR2CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL29112300 | 0.89 | HSD11B1 (0.34) | CCR2CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL24540608 | 0.87 | CYP2C19 (0.38) | CYP2C9CYP2C19CHRM2CHRM1CHRM3 | |
| SCHEMBL29112261 | 0.87 | CYP2C19 (0.38) | CYP2C9CYP2C19CHRM2CHRM1CHRM3 | |
| SCHEMBL29112263 | 0.87 | CYP2C19 (0.38) | CYP2C9CYP2C19CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263493-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | Sanofi (FR) | 2023-10-25 | — | — | EP | disclosed |
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |