SCHEMBL2454138

SCHEMBL2454138

CCOc1ccccc1/C=N/c1ccc(/C=C(\C)C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.49
▸ ALDH1A1 P00352 2/20 0.49
▸ HPGD P15428 1/20 0.49
▸ AKR1C3 P42330 1/20 0.47
▸ USP2 O75604 1/20 0.45
▸ MEN1 O00255 5/20 0.43
▸ KMT2A Q03164 5/20 0.43
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ LMNA P02545 2/20 0.42
▸ NPC1 O15118 2/20 0.41
▸ MAOB P27338 1/20 0.41
▸ PTGS1 P23219 1/20 0.41
▸ PTGS2 P35354 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ MAPT P10636 2/20 0.40
▸ HTT P42858 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ GAA P10253 1/20 0.40
▸ GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11584535 0.88 KDM4E (0.41) KDM4EALDH1A1HPGDAKR1C3USP2
SCHEMBL19281435 0.83 KDM4E (0.60) KDM4EALDH1A1HPGDUSP2MEN1
SCHEMBL11828120 0.80 KDM4E (0.56) KDM4EALDH1A1HPGDAKR1C3USP2
SCHEMBL11803780 0.80 ALDH1A1 (0.53) KDM4EALDH1A1HPGDUSP2MEN1
SCHEMBL11803784 0.80 ALDH1A1 (0.53) KDM4EALDH1A1HPGDUSP2MEN1
SCHEMBL11564421 0.75 KDM4E (0.46) KDM4EALDH1A1HPGDUSP2MEN1
SCHEMBL10533050 0.72 GAA (0.54) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL4579188 0.72 AKR1C3 (0.56) KDM4EALDH1A1AKR1C3MEN1KMT2A
SCHEMBL8415544 0.72 AKR1C3 (0.56) KDM4EALDH1A1AKR1C3MEN1KMT2A
SCHEMBL11681239 0.71 MAPT (0.61) KDM4EALDH1A1HPGDAKR1C3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 — — US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 — — US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 — — US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 — — EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 — — EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 — — US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 — — US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 — — US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 — — US disclosed
US-20170115491-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2017-04-27 — — US disclosed
US-6049366-A PLACING A LIQUID CRYSTAL FLUID COMPRISING LIQUID CRYSTAL, A PREPOLYMER, AND MICROPARTICLES BETWEEN FLEXIBLE CONDUCTIVE SUBSTRATES; LAMINATING THE SUBSTRATE TOGETHER, CURING THE FLUID LIQUID CRYSTAL COMPRISING THE PREPOLYMER SNIARICERCHE S.C.P.A. (IT) 2000-04-11 — — US disclosed
EP-0656927-B1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S C P A (IT) 1999-12-01 — — EP disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 — — EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 — — US disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 — — EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 — — EP disclosed
EP-0656927-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX Sniaricerche S.C.P.A. (IT) 1995-06-14 — — EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 — — WO disclosed
US-4005032-A Liquid crystalline composition having mixed cholesteric-nematic properties XEROX CORPORATION (US) 1977-01-25 — — US disclosed
US-3947183-A LIQUID CRYSTAL DISPLAY SYSTEM XEROX CORPORATION (US) 1976-03-30 — — US disclosed
Send feedback