SCHEMBL2454630

SCHEMBL2454630

C=COCCCCO[Si](C=C)(C=C)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2453278 0.81
SCHEMBL8850980 0.80 CDC25A (0.33)
SCHEMBL27767541 0.79 CDC25A (0.34)
SCHEMBL64718 0.79 CDC25A (0.34)
SCHEMBL8761489 0.77
SCHEMBL9721206 0.76
SCHEMBL3273399 0.76 CDC25A (0.31)
SCHEMBL18675767 0.76 ALDH1A1 (0.38)
SCHEMBL22408792 0.76 ALDH1A1 (0.38)
SCHEMBL3048726 0.76 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2132248-B1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2016-07-13 EP disclosed
US-8519038-B2 Aldimines and compositions comprising aldimine SIKA TECHNOLOGY AG (CH) 2013-08-27 US disclosed
US-20120220736-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE SIKA TECHNOLOGY AG (CH) 2012-08-30 US disclosed
US-8252859-B2 Aldimines and compositions comprising aldimine SIKA TECHNOLOGY AG (CH) 2012-08-28 US disclosed
EP-1934172-B1 COMPOUNDS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2011-09-28 EP disclosed
US-20100101455-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-04-29 US disclosed
EP-2132248-A1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN Sika Technology AG (CH) 2009-12-16 EP disclosed
US-7629433-B2 Odor-less during hydrolytic deblocking, separation; for use as source for aldehydes; crosslinking agents SIKA TECHNOLOGY AG (CH) 2009-12-08 US disclosed
US-20090176944-A1 Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof SIKA TECHNOLOGY AG (CH) 2009-07-09 US disclosed
US-20090099333-A1 Compounds Containing Aldimine SIKA TECHNOLOGY AG (CH) 2009-04-16 US disclosed
EP-2017260-A1 Aldimines and compounds containing aldimine Sika Technology AG (CH) 2009-01-21 EP disclosed
WO-2008116928-A1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2008-10-02 WO disclosed
EP-1975190-A1 Aldimines with reactive groups containing active hydrogen Sika Technology AG (CH) 2008-10-01 EP disclosed
EP-1934169-A1 ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF Sika Technology AG (CH) 2008-06-25 EP disclosed
EP-1934172-A1 COMPOUNDS CONTAINING ALDIMINE Sika Technology AG (CH) 2008-06-25 EP disclosed
EP-1775284-A1 Compounds comprising aldimine groups Sika Technology AG (CH) 2007-04-18 EP disclosed
EP-1772447-A1 Aldimines with reactive groups comprising active hydrogen, and their use Sika Technology AG (CH) 2007-04-11 EP disclosed
WO-2007036572-A1 COMPOUNDS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2007-04-05 WO disclosed
WO-2007036571-A1 ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF SIKA TECHNOLOGY AG (CH) 2007-04-05 WO disclosed