Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 6/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1511916 | 1.00 | GRM2 (0.41) | GRM2SMN1; SMN2NPSR1CCR9POLB | |
| SCHEMBL1765583 | 0.93 | GRM2 (0.41) | GRM2SMN1; SMN2NPSR1CCR9POLB | |
| SCHEMBL1765301 | 0.91 | IDH1 (0.38) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1245592 | 0.89 | GRM2 (0.52) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1511669 | 0.87 | GRM2 (0.39) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1512162 | 0.87 | GRM2 (0.39) | GRM2SMN1; SMN2NPSR1CCR9POLB | |
| SCHEMBL8007502 | 0.87 | GRM2 (0.39) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1765157 | 0.87 | GRM2 (0.39) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1511789 | 0.86 | KDM4E (0.41) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1512228 | 0.86 | GRM2 (0.38) | GRM2SMN1; SMN2NPSR1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735397-B2 | Method for treating schizophrenia and related diseases | VANDERBILT UNIVERSITY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20110237602-A1 | METHOD FOR TREATING SCHIZOPHRENIA AND RELATED DISEASES | VANDERBILT UNIVERSITY (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237602-A1 | METHOD FOR TREATING SCHIZOPHRENIA AND RELATED DISEASES | GRM2, GRIA2, GRIK2 | GRM2 1/4885SMN1; SMN2 1385/4885NPSR1 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.