Phthalic Acid

Phthalic Acid

SCHEMBL2454740

C=CC(=O)OCC(CO)(CO)COCC(CO)(COC(=O)C=C)COC(=O)C=C.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.59
HIF1A Q16665 4/20 0.59
TP53 P04637 3/20 0.59
MAPK1 P28482 2/20 0.59
CYP3A4 P08684 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
THRB P10828 2/20 0.41
ALOX15 P16050 1/20 0.38
KMT2A Q03164 3/20 0.37
PTK2B Q14289 1/20 0.37
HSD17B10 Q99714 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 4/20 0.33
HTT P42858 1/20 0.33
AKR1C3 P42330 1/20 0.33
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL234468 0.97 ALDH1A1 (0.59) ALDH1A1HIF1ATP53MAPK1CYP3A4
Phthalic Acid SCHEMBL235413 0.94 ALDH1A1 (0.67) ALDH1A1HIF1ATP53MAPK1CYP3A4
SCHEMBL20752224 0.86 ALDH1A1 (0.47) ALDH1A1HIF1ATP53MAPK1CYP3A4
Phthalic Acid SCHEMBL2454742 0.84 ALDH1A1 (0.44) ALDH1A1HIF1ATP53MAPK1CYP3A4
Phthalic Acid SCHEMBL234470 0.84 ALDH1A1 (0.44) ALDH1A1HIF1ATP53MAPK1CYP3A4
SCHEMBL12277453 0.84 ALDH1A1 (0.85) ALDH1A1HIF1ATP53MAPK1CYP3A4
SCHEMBL12277843 0.82 ALDH1A1 (0.88) ALDH1A1HIF1ATP53MAPK1CYP3A4
SCHEMBL12277839 0.82 ALDH1A1 (0.81) ALDH1A1HIF1ATP53MAPK1CYP3A4
SCHEMBL235414 0.82 ALDH1A1 (0.50) ALDH1A1HIF1ATP53MAPK1CYP3A4
SCHEMBL684275 0.81 ALDH1A1 (0.85) ALDH1A1HIF1ATP53MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1702752-B1 EMBOSSED RELEASE PAPER FOR PRODUCTION OF SYNTHETIC LEATHER, SUPPORT THEREOF, SYNTHETIC LEATHER UTILIZING THE RELEASE PAPER AND PROCESS FOR PRODUCING THE SAME DAINIPPON PRINTING CO LTD (JP) 2013-07-17 EP disclosed
EP-2380734-A1 Embrossed release sheet and apparatus and method for manufacturing same Dai Nippon Printing Co., Ltd. (JP) 2011-10-26 EP disclosed
EP-1275496-B1 LAYERED PRODUCT, BONDING METHOD, AND COMPOSITION CURABLE WITH ACTINIC ENERGY RAY MITSUBISHI CHEM CORP (JP) 2011-09-21 EP disclosed
US-20090117330-A1 ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, EMBOSSED RELEASE SHEET, METHOD FOR MANUFACTURING ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, METHOD FOR MANUFACTURING EMBOSSED RELEASE SHEET, APPARATUS FOR MANUFACTURING EMBOSSED RELEASE SHEET, SYNTHETIC LEATHER, AND METHOD FOR MANUFACTURING SYNTHETIC LEATHER DAI NIPPON PRINTING CO., LTD. (JP) 2009-05-07 US disclosed
EP-1992479-A1 ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, EMBOSSED RELEASE SHEET, METHOD FOR PRODUCING ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, METHOD FOR PRODUCING EMBOSSED RELEASE SHEET, APPARATUS FOR PRODUCING EMBOSSED RELEASE SHEET, SYNTHETIC LEATHER, AND METHOD FOR PRODUCING SYNTHETIC LEATHER Dainippon Printing Co., Ltd. (JP) 2008-11-19 EP disclosed
US-20070116929-A1 Embossed release paper for synthetic leather production and support therefor, and synthetic leather using the release paper and process for producing the synthetic leather DAI NIPPON PRINTING CO., LTD. (JP) 2007-05-24 US disclosed
EP-1702752-A1 EMBOSSED RELEASE PAPER FOR PRODUCTION OF SYNTHETIC LEATHER, SUPPORT THEREOF, SYNTHETIC LEATHER UTILIZING THE RELEASE PAPER AND PROCESS FOR PRODUCING THE SAME Dainippon Printing Co., Ltd. (JP) 2006-09-20 EP disclosed
US-20030118838-A1 Laminate, adhering method and active energy ray-curable composition MITSUBISHI CHEMICAL CORPORATION (JP) 2003-06-26 US disclosed
EP-1275496-A1 LAYERED PRODUCT, BONDING METHOD, AND COMPOSITION CURABLE WITH ACTINIC ENERGY RAY MITSUBISHI CHEMICAL CORPORATION (JP) 2003-01-15 EP disclosed