Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203873 | 0.80 | ELANE (0.36) | ELANEHTR5A | |
| SCHEMBL9203871 | 0.76 | ELANE (0.36) | ELANEHTR5A | |
| SCHEMBL23139056 | 0.75 | ELANE (0.35) | ELANEHTR5A | |
| SCHEMBL939412 | 0.72 | PDE4D (0.30) | — | |
| SCHEMBL25626368 | 0.72 | ELANE (0.33) | ELANE | |
| SCHEMBL24547702 | 0.66 | CNR2 (0.33) | — | |
| SCHEMBL16661986 | 0.65 | SYK (0.31) | ELANE | |
| SCHEMBL24547508 | 0.65 | — | — | |
| SCHEMBL21401233 | 0.64 | PDE4D (0.31) | — | |
| SCHEMBL22002403 | 0.64 | PDE4D (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129331-A1 | MACROCYCLIC BRANCHED 3-FLUORO-BUT-3-ENAMIDES AS INHIBITORS OF MCL-1 | JANSSEN PHARMACEUTICA NV (BE) | 2022-06-23 | — | — | WO | disclosed |