Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23139056 | 0.83 | ELANE (0.35) | ELANEHTR5ASPHK1 | |
| SCHEMBL5153335 | 0.80 | NPC1 (0.34) | HPGDS | |
| SCHEMBL24547484 | 0.80 | ELANE (0.35) | ELANEHTR5A | |
| SCHEMBL25626368 | 0.79 | ELANE (0.33) | ELANE | |
| SCHEMBL9203871 | 0.79 | ELANE (0.36) | ELANEHTR5A | |
| SCHEMBL20064251 | 0.77 | TSHR (0.36) | HPGDS | |
| SCHEMBL1371751 | 0.76 | GPR119 (0.32) | — | |
| SCHEMBL11312585 | 0.75 | SLC6A2 (0.33) | HPGDS | |
| SCHEMBL9188420 | 0.75 | MEN1 (0.45) | HPGDS | |
| SCHEMBL17802205 | 0.75 | HPGDS (0.33) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382213-B1 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5053548-A | Containing hydroxy substituents; nervous system disorders | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0382213-A2 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |