Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17502528 | 0.98 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL14506690 | 0.90 | KMT2A (0.46) | NPC1RAB9ASMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL25039539 | 0.90 | KDM1A (0.53) | NPC1RAB9ASMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL1704674 | 0.86 | KDM1A (0.53) | NPC1RAB9ASMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL31453688 | 0.84 | KMT2A (0.59) | KMT2ARAPGEF4MEN1ALDH1A1 | |
| SCHEMBL9008342 | 0.84 | KMT2A (0.59) | KMT2ARAPGEF4MEN1ALDH1A1 | |
| SCHEMBL9442760 | 0.84 | KCNQ3 (0.40) | NPC1RAB9ASMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL29218593 | 0.79 | KCNQ3 (0.47) | NPC1RAB9ASMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL17048125 | 0.79 | KMT2A (0.47) | RAB9APTGS1PTGS2KMT2APOLB | |
| SCHEMBL6559446 | 0.79 | KDM1A (0.47) | NPC1RAB9ASMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582906-A | Difluorophenyl ring propylamine compound and preparation method and application thereof | 郑州大学 | 2021-11-02 | — | — | CN | claimed |
| CN-109553622-A | A kind of preparation method of ticagrelor impurity | 扬子江药业集团有限公司 | 2019-04-02 | — | — | CN | claimed |
| WO-2017072790-A1 | AN IMPROVED PROCESS FOR SYNTHESIS OF TICAGRELOR | AVRA LABORATORIES PVT. LTD. (IN) | 2017-05-04 | — | — | WO | claimed |
| EP-2588441-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | Actavis Group Ptc Ehf (IS) | 2013-05-08 | — | — | EP | claimed |
| WO-2012001531-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2012-01-05 | — | — | WO | claimed |
| EP-0990639-B1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL IND CO (JP) | 2004-02-25 | — | — | EP | claimed |
| US-6162944-A | Process for production of N-cyclopropylanilines and intermediates therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-12-19 | — | — | US | claimed |
| EP-0990639-A1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-04-05 | — | — | EP | claimed |
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | Jubilant Epicore LLC (US) | 2025-11-25 | — | — | US | disclosed |
| EP-3455204-B1 | CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS | Jubilant Epicore LLC (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-3955929-B1 | NEW PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF GRAM-NEGATIVE BACTERIAL INFECTION, CONTAMINATION AND FOULING | UNIV LIEGE (BE) | 2024-05-15 | — | — | EP | disclosed |
| CN-115368245-B | Preparation method of hydrochloride crystal form of (1R, 2S) - (3, 4-difluorophenyl) cyclopropylamine | 上海医药工业研究院 | 2024-03-22 | — | — | CN | disclosed |
| CN-115368245-B | Preparation method of hydrochloride crystal form of (1R, 2S) - (3, 4-difluorophenyl) cyclopropylamine | 上海医药工业研究院 | 2024-03-22 | — | — | CN | disclosed |
| CN-115368245-B | Preparation method of hydrochloride crystal form of (1R, 2S) - (3, 4-difluorophenyl) cyclopropylamine | 上海医药工业研究院 | 2024-03-22 | — | — | CN | disclosed |
| EP-0990639-A4 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL IND CO (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6162944-A | Process for production of N-cyclopropylanilines and intermediates therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| US-6162944-A | Process for production of N-cyclopropylanilines and intermediates therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0990639-A1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
| EP-0990639-A1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-1999050226-A1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | HDAC1, HDAC11, HDAC2 | NPC1 297/4885RAB9A 1828/4885SMN1; SMN2 1068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.