SCHEMBL9008342

SCHEMBL9008342

Fc1ccc(NC2CC2)cc1Cl

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
MEN1 O00255 3/20 0.59
ALDH1A1 P00352 3/20 0.59
MAPT P10636 2/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TRPA1 O75762 1/20 0.50
NR1I2 O75469 1/20 0.50
AHR P35869 1/20 0.50
RAPGEF4 Q8WZA2 1/20 0.49
KCNH2 Q12809 1/20 0.47
CDK2 P24941 3/20 0.46
MAPKAPK2 P49137 3/20 0.46
SLC2A1 P11166 1/20 0.46
GAA P10253 1/20 0.46
ROCK2 O75116 1/20 0.45
MAPK9 P45984 1/20 0.45
GSK3B P49841 1/20 0.45
MAP2K1 Q02750 1/20 0.45
MAPKAPK5 Q8IW41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31453688 1.00 KMT2A (0.59) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL245476 0.84 NPC1 (0.49) KMT2AMEN1ALDH1A1RAPGEF4
Hydrochloric Acid SCHEMBL17502528 0.82 NPC1 (0.47) KMT2AMEN1ALDH1A1RAPGEF4
SCHEMBL27687355 0.78 UBE2M (0.55) HTTHPGD
SCHEMBL8573402 0.77 KMT2A (0.43) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL8574181 0.77 MAPKAPK2 (0.44) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL8572544 0.77 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL1470632 0.77 MEN1 (0.52) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL9442760 0.77 KCNQ3 (0.40) KMT2AMEN1ALDH1A1CDK2MAPKAPK2
SCHEMBL25039539 0.76 KDM1A (0.53) KMT2ARAPGEF4KCNH2CDK2MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122103024-A Ciprofloxacin intermediate compound and preparation method and application thereof 2026-05-29 CN disclosed
EP-0738257-A1 NEW METHOD FOR N-CYCLOPROPYLATION OF AROMATIC AMINES, AS WELL AS COMPOUNDS AND COMPOSITIONS OBTAINED SOMFAI, Eva, Dr. (HU) 1996-10-23 EP disclosed
WO-1995002573-A2 NEW METHOD FOR N-CYCLOPROPYLATION OF AROMATIC AMINES, AS WELL AS COMPOUNDS AND COMPOSITIONS OBTAINED SOMFAI EVA (HU) 1995-01-26 WO disclosed
EP-0430847-A1 Procedure for the preparation of N-cyclopropyl-4-fluoroanilines CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) 1991-06-05 EP disclosed
EP-0376870-A1 A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) 1990-07-04 EP disclosed