Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24549239 | 0.88 | BTK (0.42) | SYKBTKKDRPTGES | |
| SCHEMBL24549464 | 0.88 | SYK (0.37) | SYKBTKKCNH2KDRJAK2 | |
| SCHEMBL29653718 | 0.88 | SYK (0.37) | SYKBTKKCNH2KDRJAK2 | |
| SCHEMBL24549228 | 0.87 | SYK (0.38) | SYKBTKKCNH2KDRPTGES | |
| SCHEMBL24549235 | 0.87 | SYK (0.38) | SYKBTKKCNH2KDRJAK2 | |
| SCHEMBL24549232 | 0.85 | KCNH2 (0.44) | SYKBTKKCNH2KDR | |
| SCHEMBL24549233 | 0.84 | SYK (0.35) | SYKBTKKCNH2KDRPTGES | |
| SCHEMBL29132128 | 0.84 | SYK (0.39) | SYKBTKKDR | |
| SCHEMBL24548979 | 0.84 | SYK (0.36) | SYKBTKKCNH2KDRPTGES | |
| SCHEMBL29653762 | 0.84 | SYK (0.36) | SYKBTKKCNH2KDRPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133098-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |