Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30750851 | 0.94 | SYK (0.37) | SYKPDE10ABTKPRKAA1PRKAB2 | |
| SCHEMBL24549087 | 0.94 | SYK (0.37) | SYKPDE10ABTKPRKAA1PRKAB2 | |
| SCHEMBL29132128 | 0.90 | SYK (0.39) | SYKBTKKDR | |
| SCHEMBL24549239 | 0.90 | BTK (0.42) | SYKBTKKDRKCNN1KCNN2 | |
| SCHEMBL24549228 | 0.89 | SYK (0.38) | SYKBTKKDRSOS1KCNN1 | |
| SCHEMBL30750865 | 0.89 | PRKAB2 (0.39) | SYKPDE10ABTKPRKAA1PRKAB2 | |
| SCHEMBL24549466 | 0.89 | PRKAB2 (0.39) | SYKPDE10ABTKPRKAA1PRKAB2 | |
| SCHEMBL29132135 | 0.88 | SYK (0.39) | SYKBTKPRKAA1PRKAB2PRKAG1 | |
| SCHEMBL24549464 | 0.87 | SYK (0.37) | SYKBTKKDRJAK2TBK1 | |
| SCHEMBL29653718 | 0.87 | SYK (0.37) | SYKBTKKDRJAK2TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051970-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2024-02-15 | — | — | US | disclosed |
| WO-2022133098-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051970-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | SYK 727/4885PDE10A 323/4885BTK 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.