Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 11/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748120 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2KIF11PDE2APDE10ACYP1A2 | |
| SCHEMBL15727582 | 0.81 | KDM4E (0.50) | KIF11PDE2APDE10APDE7ABACE1 | |
| SCHEMBL30039988 | 0.81 | KDM4E (0.50) | KIF11PDE2APDE10APDE7ABACE1 | |
| SCHEMBL11872026 | 0.78 | S1PR1 (0.45) | KIF11CYP2C19S1PR1 | |
| SCHEMBL2634929 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2PDE2APDE10A | |
| SCHEMBL28285676 | 0.76 | KDM4E (0.55) | SMN1; SMN2KIF11PDE2APDE10APDE7A | |
| SCHEMBL8451109 | 0.75 | CNR2 (0.49) | SMN1; SMN2PDE2APDE10ACYP1A2CYP2D6 | |
| SCHEMBL175367 | 0.74 | MEN1 (0.57) | KIF11PDE2APDE10ACYP2C19PDE7A | |
| SCHEMBL28712778 | 0.74 | KIF11 (0.40) | KIF11PDE2APDE10ACYP1A2CYP2D6 | |
| SCHEMBL4539855 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768761-B | Novel benzimidazole derivatives | 卡尔那生物科学株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115768761-A | Novel benzimidazole derivatives | 卡尔那生物科学株式会社 | 2023-03-07 | — | — | CN | disclosed |
| WO-2022133098-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |