Dihydrocaffeic Acid

Dihydrocaffeic Acid

SCHEMBL245530

O=C(O)CCc1ccc(O)c(O)c1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 3/20 0.65
KDM4E B2RXH2 3/20 0.64
MAPT P10636 3/20 0.64
GAA P10253 2/20 0.64
APEX1 P27695 2/20 0.64
THPO P40225 2/20 0.64
HIF1A Q16665 2/20 0.64
HSD17B10 Q99714 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
RGS12 O14924 1/20 0.64
LMNA P02545 1/20 0.64
POLB P06746 1/20 0.64
HPGD P15428 1/20 0.64
TSHR P16473 1/20 0.64
NFKB1 P19838 1/20 0.64
BLM P54132 1/20 0.64
GNAI1 P63096 1/20 0.64
PMP22 Q01453 1/20 0.64
LCK P06239 1/20 0.61
APP P05067 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydrocaffeic Acid SCHEMBL7058919 1.00 IAPP (0.65) IAPPKDM4EMAPTGAAAPEX1
Dihydrocaffeic Acid SCHEMBL29351390 1.00 IAPP (0.65) IAPPKDM4EMAPTGAAAPEX1
Dihydrocaffeic Acid SCHEMBL31017610 0.93 IAPP (0.57) IAPPKDM4EMAPTGAAAPEX1
Dihydrocaffeic Acid SCHEMBL15520737 0.91 KDM4E (0.56) IAPPKDM4EMAPTGAAAPEX1
Dihydrocaffeic Acid SCHEMBL175650 0.89 KDM4E (0.55) IAPPKDM4EMAPTGAAAPEX1
SCHEMBL18788836 0.88 IGF1R (0.67) IAPPKDM4EMAPTGAAAPEX1
SCHEMBL17938812 0.86 IGF1R (0.70) IAPPKDM4EMAPTGAAAPEX1
SCHEMBL31672999 0.86 IGF1R (0.70) IAPPKDM4EMAPTGAAAPEX1
Hydroxytyrosol SCHEMBL28182739 0.86 KDM4E (0.74) IAPPKDM4EMAPTGAAAPEX1
SCHEMBL9634006 0.86 CNR1 (0.57) IAPPKDM4EMAPTGAAAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3248 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-122017093-A Method for rapidly determining various phenolic acid substances in fermentation product 安徽古井贡酒股份有限公司 2026-05-12 CN claimed
US-12616771-B2 Tissue adherent chitosan material that resists dissolution TRICOL BIOMEDICAL, INC. (US) 2026-05-05 US claimed
US-20260097148-A1 HYDROPHOBICALLY-MODIFIED POLYMERS WITH BENZENEDIOL FUNCTIONAL GROUPS AND OXIDIZED FORMS THEREOF MEDCURA INC (US) 2026-04-09 US claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
WO-2026044024-A1 COMPOSITIONS COMPRISING COMBINATIONS OF PHARMACEUTICALLY ACCEPTABLE SALTS AND OTHER DERIVATIVES OF GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND PHARMACEUTICALLY ACCEPTABLE SALTS AND OTHER DERIVATIVES OF AMYLIN ANALOG, AND USES THEREOF I2O THERAPEUTICS, INC. (US) 2026-02-26 WO claimed
US-20260041183-A1 ADHESIVE FOR COSMETIC ARTICLE AND METHOD OF FORMING FULLER H B CO (US) 2026-02-12 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
EP-0418065-B1 Dihydrocaffeic acid derivatives, use thereof for medical treatments and pharmaceutical preparations containing same MITSUI TOATSU CHEMICALS (JP) 1994-04-20 EP claimed
US-5290793-A Alzheimer's disease; induc nerve growth factor production MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-03-01 US claimed
EP-0495998-A1 DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-07-29 EP claimed
US-5116979-A Alzheimer*s disease; induces secretion of nerve growth factor MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-05-26 US claimed
EP-0418065-A2 Dihydrocaffeic acid derivatives, use thereof for medical treatments and pharmaceutical preparations containing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-03-20 EP claimed
EP-0357565-A2 New process for the synthesis of the levodopa MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1990-03-07 EP claimed
EP-0170893-B1 MICROBIOCIDAL ANIONIC SEQUESTERANTS WITH POLYVALENT METAL CATIONS FOR PERMEABILITY CORRECTION PROCESS PHILLIPS PETROLEUM COMPANY (US) 1989-08-30 EP claimed
US-4629747-A INCLUDES CROSSLINKABLE WATER SOLUBLE POLYMER PHILLIPS PETROLEUM COMPANY (US) 1986-12-16 US claimed
EP-0170893-A1 Microbiocidal anionic sequesterants with polyvalent metal cations for permeability correction process PHILLIPS PETROLEUM COMPANY (US) 1986-02-12 EP claimed
US-4552217-A Microbiocidal anionic sequesterants with polyvalent metal cations for permeability correction process PHILLIPS PETROLEUM COMPANY (US) 1985-11-12 US claimed