Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683210 | 1.00 | CSNK1D (0.40) | CSNK1DTHRBMAPK14CSNK1A1TLR9 | |
| SCHEMBL29683181 | 0.85 | ADORA2A (0.42) | CSNK1DTHRBMAPK14TLR9TLR8 | |
| SCHEMBL24553831 | 0.85 | TLR9 (0.46) | THRBMAPK14TLR9TLR8TLR7 | |
| SCHEMBL24553883 | 0.85 | ADORA2A (0.42) | CSNK1DTHRBMAPK14TLR9TLR8 | |
| SCHEMBL24554419 | 0.83 | ADORA2A (0.43) | CSNK1DTHRBMAPK14ADORA2AADORA2B | |
| SCHEMBL29683052 | 0.83 | ADORA2A (0.43) | CSNK1DTHRBMAPK14ADORA2AADORA2B | |
| SCHEMBL26645677 | 0.82 | ADORA2A (0.44) | CSNK1DTHRBMAPK14ADORA2A | |
| SCHEMBL24554415 | 0.82 | MAPK14 (0.53) | CSNK1DTHRBMAPK14CSNK1A1ADORA2A | |
| SCHEMBL29683384 | 0.81 | CSNK1D (0.37) | CSNK1DTHRBMAPK14ADORA2AADORA2B | |
| SCHEMBL24554297 | 0.81 | CSNK1D (0.37) | CSNK1DTHRBMAPK14ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127756-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |