Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24553831 | 0.86 | TLR9 (0.46) | ADORA2AMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL25221948 | 0.85 | TLR9 (0.40) | ADORA2ACSNK1DCSNK1ETHRB | |
| SCHEMBL29683181 | 0.84 | ADORA2A (0.42) | ADORA2AMAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL24553883 | 0.84 | ADORA2A (0.42) | ADORA2AMAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL30579567 | 0.82 | SREBF2 (0.44) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL24554221 | 0.82 | CSNK1D (0.40) | ADORA2AMAPK14CSNK1DTHRB | |
| SCHEMBL29683052 | 0.82 | ADORA2A (0.43) | ADORA2AMAPK14CSNK1DTHRB | |
| SCHEMBL24554419 | 0.82 | ADORA2A (0.43) | ADORA2AMAPK14CSNK1DTHRB | |
| SCHEMBL29683210 | 0.82 | CSNK1D (0.40) | ADORA2AMAPK14CSNK1DTHRB | |
| SCHEMBL7494623 | 0.81 | MAPK14 (0.43) | ADORA2AMAPK14CSNK1DCSNK1EMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |