Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KIF20A | O95235 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682755 | 1.00 | TUBB1 (0.60) | TUBB1MAPTSMN1; SMN2TP53NPSR1 | |
| SCHEMBL21438666 | 0.85 | AHR (0.63) | MAPTSMN1; SMN2TP53NPSR1AHR | |
| SCHEMBL21449261 | 0.79 | NR4A2 (0.57) | TUBB1MAPTSMN1; SMN2TP53NPSR1 | |
| SCHEMBL21438565 | 0.78 | NR4A2 (0.67) | TUBB1MAPTSMN1; SMN2TP53NPSR1 | |
| SCHEMBL1563040 | 0.77 | TUBB1 (0.78) | TUBB1MAPTSMN1; SMN2TP53NPSR1 | |
| SCHEMBL590922 | 0.76 | MAPT (0.73) | TUBB1MAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL30075344 | 0.76 | MAPT (0.73) | TUBB1MAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL1562290 | 0.76 | TUBB1 (1.00) | TUBB1MAPTSMN1; SMN2TP53NPSR1 | |
| SCHEMBL12480809 | 0.75 | MAPT (0.71) | TUBB1MAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL1563760 | 0.75 | TUBB1 (0.70) | TUBB1MAPTSMN1; SMN2TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133480-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |