⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355099 | 0.81 | — | — | |
| SCHEMBL11972321 | 0.75 | — | — | |
| SCHEMBL1515499 | 0.75 | — | — | |
| SCHEMBL10002460 | 0.75 | — | — | |
| SCHEMBL4065197 | 0.75 | — | — | |
| SCHEMBL517143 | 0.75 | — | — | |
| SCHEMBL517144 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL12538845 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL12538843 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL15968078 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317775-A1 | H4 Antagonist Compounds | NXERA PHARMA UK LIMITED (GB) | 2024-09-26 | — | — | US | disclosed |
| EP-4259637-A1 | H4 ANTAGONIST COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-10-18 | — | — | EP | disclosed |
| CN-116848125-A | H4 antagonist compounds | 赫帕雷斯治疗有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022129890-A1 | H4 ANTAGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129890-A1 | H4 ANTAGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |