SCHEMBL2455473

SCHEMBL2455473

CCOc1ccc(C=Nc2ccc(C#N)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.51
▸ ALDH1A1 P00352 6/20 0.46
▸ GAA P10253 4/20 0.46
▸ MEN1 O00255 4/20 0.46
▸ KDM4E B2RXH2 3/20 0.46
▸ MAPT P10636 3/20 0.46
▸ PKM P14618 2/20 0.46
▸ CASP3 P42574 2/20 0.46
▸ SENP7 Q9BQF6 2/20 0.46
▸ SENP6 Q9GZR1 2/20 0.46
▸ THRB P10828 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ BLM P54132 1/20 0.46
▸ PLEC Q15149 1/20 0.46
▸ SENP8 Q96LD8 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ S100B P04271 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ USP2 O75604 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12416678 1.00 KMT2A (0.51) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL2455471 1.00 KMT2A (0.51) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL11675092 1.00 KMT2A (0.51) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL12416627 0.89 KMT2A (0.57) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL19460778 0.89 KMT2A (0.57) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL11592127 0.88 MEN1 (0.55) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL3084005 0.88 ALDH1A1 (0.52) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL12417135 0.88 MEN1 (0.55) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL12416685 0.88 ALDH1A1 (0.52) KMT2AALDH1A1GAAMEN1KDM4E
SCHEMBL3085595 0.88 ALDH1A1 (0.52) KMT2AALDH1A1GAAMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4153343-A Liquid crystal dyestuffs and electro-optic devices incorporating same RCA CORPORATION (US) 1979-05-08 — — US claimed
US-4076646-A O- OR M-TERPHENYLS HITACHI, LTD. (JA) 1978-02-28 — — US claimed
US-4018507-A Liquid crystal device, composition therefor, and method for preparing the composition AMERICAN MICRO-SYSTEMS, INC. (US) 1977-04-19 — — US claimed
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 — — US disclosed
EP-3469576-B1 MULTI-LAYER DISPLAY WITH COLOR AND CONTRAST ENHANCEMENT SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 — — EP disclosed
CN-109478389-B Multi-layer display with color and contrast enhancement 三星电子株式会社 2023-01-10 — — CN disclosed
CN-109477972-B Multi-layer high transparency display for light field generation 三星电子株式会社 2022-02-22 — — CN disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 — — US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 — — US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 — — US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 — — EP disclosed
US-4058476-A NEMATIC, DIELECTRIC HOFFMANN-LA ROCHE INC. (US) 1977-11-15 — — US disclosed
US-4035060-A Electro-optic device DAINIPPON PRINTING CO., LTD (JA) 1977-07-12 — — US disclosed
US-4018507-A Liquid crystal device, composition therefor, and method for preparing the composition AMERICAN MICRO-SYSTEMS, INC. (US) 1977-04-19 — — US disclosed
US-3997242-A Electro-optical cell containing dielectric isonitriles HOFFMANN-LA ROCHE INC. (US) 1976-12-14 — — US disclosed
US-3983049-A Liquid crystal compositions with positive dielectric anisotropy GENERAL ELECTRIC COMPANY (US) 1976-09-28 — — US disclosed
US-3963311-A Liquid crystal esters HOFFMANN-LA ROCHE INC. (US) 1976-06-15 — — US disclosed
US-3955187-A Proportioning the address and data signals in a r.m.s. responsive display device matrix to obtain zero cross-talk and maximum contrast GENERAL ELECTRIC COMPANY (US) 1976-05-04 — — US disclosed
US-3944330-A Electro-optic device DAINIPPON PRINTING CO., LTD. (JA) 1976-03-16 — — US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 — — US disclosed
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