Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2C | Q8TBX8 | 10/20 | 0.82 |
| ▸ | PIP4K2A | P48426 | 4/20 | 0.69 |
| ▸ | PIP4K2B | P78356 | 4/20 | 0.69 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.69 |
| ▸ | CDK7 | P50613 | 4/20 | 0.49 |
| ▸ | CCNH | P51946 | 4/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24558485 | 0.92 | PIP4K2C (0.80) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL24558481 | 0.86 | PIP4K2C (0.75) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL20087925 | 0.82 | PIP4K2A (1.00) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL18340770 | 0.82 | PIP4K2A (0.84) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL30107628 | 0.82 | PIP4K2A (1.00) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL24558494 | 0.80 | PIP4K2C (0.65) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL24558504 | 0.78 | PIP4K2C (0.67) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL24558500 | 0.78 | PIP4K2C (0.60) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK2 | |
| SCHEMBL15648481 | 0.75 | PIP4K2C (0.58) | PIP4K2CPIP4K2APIP4K2BPIKFYVECDK7 | |
| SCHEMBL1244782 | 0.73 | PIP4K2C (0.57) | PIP4K2CPIP4K2APIP4K2BPIKFYVECCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140554-A1 | SMALL MOLECULE DEGRADERS OF PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE 2 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-30 | — | — | WO | disclosed |