Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 9/20 | 1.00 |
| ▸ | PIP4K2B | P78356 | 9/20 | 1.00 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 1.00 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 1.00 |
| ▸ | CDK7 | P50613 | 9/20 | 0.75 |
| ▸ | CCNH | P51946 | 9/20 | 0.75 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.68 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.68 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.68 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.68 |
| ▸ | CCNK | O75909 | 1/20 | 0.68 |
| ▸ | CDK1 | P06493 | 1/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.68 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.68 |
| ▸ | CDK2 | P24941 | 1/20 | 0.68 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.68 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.68 |
| ▸ | CDK9 | P50750 | 1/20 | 0.68 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.68 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20087925 | 1.00 | PIP4K2A (1.00) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL18340770 | 0.91 | PIP4K2A (0.84) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL17710604 | 0.87 | CDK7 (0.77) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL17710603 | 0.87 | CDK7 (0.77) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL18313434 | 0.86 | CDK7 (1.00) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL17710592 | 0.84 | CDK7 (0.80) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL17710591 | 0.84 | CDK7 (0.80) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL24558484 | 0.82 | PIP4K2C (0.82) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL18340746 | 0.82 | PIP4K2A (0.81) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 | |
| SCHEMBL18340744 | 0.82 | PIP4K2A (0.81) | PIP4K2APIP4K2BPIP4K2CPIKFYVECDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230096781-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | UNIVERSITY OF CINCINNATI (US) | 2023-03-30 | — | — | US | claimed |
| EP-4114963-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | University of Cincinnati (US) | 2023-01-11 | — | — | EP | claimed |
| WO-2023150147-A1 | METHOD OF PREVENTING HEARING LOSS | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20230096781-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | UNIVERSITY OF CINCINNATI (US) | 2023-03-30 | — | — | US | disclosed |
| EP-4114963-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | University of Cincinnati (US) | 2023-01-11 | — | — | EP | disclosed |