Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | VHL | P40337 | 18/20 | 0.35 |
| ▸ | ELOC | Q15369 | 6/20 | 0.35 |
| ▸ | ELOB | Q15370 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24239716 | 0.91 | DPP4 (0.35) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL22138808 | 0.87 | DPP4 (0.40) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL24474127 | 0.86 | VHL (0.40) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL26725347 | 0.86 | DPP4 (0.36) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL21554539 | 0.85 | VHL (0.41) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL21759977 | 0.85 | VHL (0.38) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL23183583 | 0.85 | VHL (0.41) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL21554505 | 0.85 | VHL (0.41) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL20419046 | 0.85 | VHL (0.41) | DPP4DPP8DPP9VHLELOC | |
| SCHEMBL22138839 | 0.83 | VHL (0.41) | DPP4DPP8DPP9VHLELOC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140554-A1 | SMALL MOLECULE DEGRADERS OF PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE 2 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-30 | — | — | WO | disclosed |