SCHEMBL2456070

SCHEMBL2456070

C=Cc1ccccc1N1CCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 2/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ GFER P55789 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ APOBEC3A P31941 1/20 0.39
▸ APOBEC3G Q9HC16 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ ALOX5AP P20292 1/20 0.37
▸ FEN1 P39748 1/20 0.37
▸ MGLL Q99685 1/20 0.37
▸ KDM4E B2RXH2 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16382666 0.95 GFER (0.39) TP53HSD17B10GFERALDH1A1APOBEC3A
SCHEMBL28312376 0.85 MEN1 (0.48) TP53HSD17B10GFERALDH1A1APOBEC3A
SCHEMBL27704929 0.81 HSD17B10 (0.42) HSD17B10ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL7667197 0.78 TP53 (0.39) TP53HSD17B10GFERALDH1A1APOBEC3A
SCHEMBL3842955 0.77 HSD17B10 (0.44) TP53HSD17B10GFERALDH1A1APOBEC3A
SCHEMBL10363439 0.76 APOBEC3A (0.44) TP53HSD17B10GFERALDH1A1APOBEC3A
SCHEMBL7787664 0.75 HSD17B10 (0.53) TP53HSD17B10GFERALDH1A1APOBEC3A
SCHEMBL5792793 0.75 MEN1 (0.38) HSD17B10ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL7664279 0.74 L3MBTL1 (0.37) TP53HSD17B10GFERALDH1A1APOBEC3A
SCHEMBL22997585 0.74 HSD17B10 (0.44) TP53HSD17B10GFERALDH1A1APOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761587-B1 PLASTISOLS BASED ON A METHYLMETHACRYLATE COPOLYMER EVONIK ROEHM GMBH (DE) 2010-01-20 — — EP claimed
US-20220024102-A1 Acrylic foils with improved UV-protection properties RÖHM GMBH (DE) 2022-01-27 — — US disclosed
EP-3659798-B1 ACRYLIC FOILS WITH IMPROVED UV-PROTECTION PROPERTIES ROEHM GMBH (DE) 2021-09-08 — — EP disclosed
CN-113165359-A Acrylic films with improved UV protection 罗姆化学有限责任公司 2021-07-23 — — CN disclosed
CN-110049869-B Extruded matte foil with improved mechanical properties and high weatherability 罗姆化学有限责任公司 2021-05-07 — — CN disclosed
EP-3659798-A1 ACRYLIC FOILS WITH IMPROVED UV-PROTECTION PROPERTIES Röhm GmbH (DE) 2020-06-03 — — EP disclosed
US-10611130-B2 Extruded matt foil with improved mechanical properties and a high weathering resistance RÖHM GMBH (DE) 2020-04-07 — — US disclosed
EP-3353238-B1 EXTRUDED MATT FOIL WITH IMPROVED MECHANICAL PROPERTIES AND A HIGH WEATHERING RESISTANCE EVONIK ROEHM GMBH (DE) 2018-09-26 — — EP disclosed
EP-2886619-A1 Compound with improved adhesion Evonik Industries AG (DE) 2015-06-24 — — EP disclosed
EP-1846239-B1 FILM MEMBRANE WITH EXCELLENT WEATHER-RESISTANT PROPERTIES, HIGH TRANSMISSION OF SOLAR THERMAL RADIATION, EFFECTIVE RETENTION OF THERMAL RADIATION EMITTED BY THE EARTH AND HIGH DEGREE OF MECHANICAL STRENGTH AND METHOD FOR PRODUCING SAID FILM MEMBRANE EVONIK ROEHM GMBH (DE) 2012-08-15 — — EP disclosed
EP-1382634-A2 Plastisol-Composition Röhm GmbH & Co. KG (DE) 2004-01-21 — — EP disclosed
EP-0947558-B1 Poly(meth)acrylic resins with high molecular weight for use in plastisols ROEHM GMBH (DE) 2003-08-20 — — EP disclosed
US-6498209-B1 EMULSION POLYMERIZED HOMOPOLYMERS OR COPOLYMERS; SUPERIOR SHELF LIFE, TENSILE STRENGTH EXTENSIBILITY, VISCOSITY, GEL FORMATION AND FILM FORMING ROEHM GMBH & CO. KG (DE) 2002-12-24 — — US disclosed
EP-1167445-A2 Foamable poly(meth)acrylate plastisol, and process for preparing it Röhm GmbH & Co. KG (DE) 2002-01-02 — — EP disclosed
EP-0947558-A1 Poly(meth)acrylic resins with high molecular weight for use in plastisols Degussa-Hüls Aktiengesellschaft (DE) 1999-10-06 — — EP disclosed
EP-0774483-A2 Plastisols based on plasticizer treated polymers RÖHM GMBH (DE) 1997-05-21 — — EP disclosed
EP-0477708-B1 Thermically film forming matter based on polymethacrylate and plasticized by addition of plasticizer ROEHM GMBH (DE) 1997-04-23 — — EP disclosed
EP-0612788-A1 Improved plastisols Röhm GmbH (DE) 1994-08-31 — — EP disclosed
EP-0533026-A2 Plastisol system exhibiting improved adhesion RÖHM GMBH (DE) 1993-03-24 — — EP disclosed
EP-0477708-A2 Thermically film forming matter based on polymethacrylate and plasticized by addition of plasticizer RÖHM GMBH (DE) 1992-04-01 — — EP disclosed
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