Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 9/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | NPM1 | P06748 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565257 | 0.89 | MAP4K1 (0.52) | EGFRMAP4K1ALKIGF1RMAPK8 | |
| SCHEMBL24565166 | 0.86 | EGFR (0.55) | BRD4EGFRALK | |
| SCHEMBL24565262 | 0.81 | MAP4K1 (0.57) | MAP4K1PTK2IGF1RMAPK8 | |
| SCHEMBL24565466 | 0.80 | ALK (0.55) | EGFRALK | |
| SCHEMBL24565252 | 0.77 | ALK (0.41) | BRD4EGFRMAP4K1PTK2ALK | |
| SCHEMBL24565236 | 0.75 | IGF1R (0.58) | MAP4K1PTK2IGF1RMAPK8 | |
| SCHEMBL24565302 | 0.75 | IGF1R (0.47) | EGFRMAP4K1PTK2IGF1RMAPK8 | |
| SCHEMBL24565333 | 0.74 | ALK (0.44) | EGFRMAP4K1PTK2ALK | |
| SCHEMBL24565244 | 0.73 | IGF1R (0.59) | MAP4K1PTK2IGF1RMAPK8 | |
| SCHEMBL24565269 | 0.72 | ALK (0.60) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |