Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 8/20 | 0.55 |
| ▸ | MET | P08581 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 12/20 | 0.50 |
| ▸ | ROS1 | P08922 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565166 | 0.94 | EGFR (0.55) | ALKMETEGFRROS1FLT3 | |
| SCHEMBL24565269 | 0.89 | ALK (0.60) | ALKMETEGFRROS1FLT3 | |
| SCHEMBL24565479 | 0.87 | ROS1 (0.59) | ALKMETEGFRROS1LRRK2 | |
| SCHEMBL24565194 | 0.87 | ALK (0.57) | ALKMETEGFRROS1FLT3 | |
| SCHEMBL1038584 | 0.86 | ALK (0.61) | ALKMETEGFRROS1FLT3 | |
| SCHEMBL24565276 | 0.86 | ALK (0.61) | ALKMETEGFRROS1FLT3 | |
| SCHEMBL24565201 | 0.83 | ROS1 (0.59) | ALKMETEGFRROS1LRRK2 | |
| SCHEMBL541915 | 0.83 | ALK (0.69) | ALKMETEGFRROS1FLT3 | |
| SCHEMBL1035873 | 0.83 | ALK (0.67) | ALKMETEGFRROS1FLT3 | |
| SCHEMBL12726512 | 0.81 | ALK (0.63) | ALKMETEGFRROS1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |