Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 13/20 | 0.52 |
| ▸ | TTK | P33981 | 1/20 | 0.49 |
| ▸ | GRK5 | P34947 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565465 | 0.87 | PTK2 (0.55) | PTK2 | |
| SCHEMBL24565236 | 0.78 | IGF1R (0.58) | IGF1RMAPK8MAP4K1PTK2TTK | |
| SCHEMBL24565324 | 0.78 | IGF1R (0.59) | IGF1RMAPK8MAP4K1TTKGRK5 | |
| SCHEMBL24565244 | 0.77 | IGF1R (0.59) | IGF1RMAPK8MAP4K1PTK2TTK | |
| SCHEMBL24565262 | 0.75 | MAP4K1 (0.57) | IGF1RMAPK8MAP4K1PTK2GRK5 | |
| SCHEMBL24565332 | 0.75 | ALK (0.48) | IGF1RMAP4K1 | |
| SCHEMBL24565184 | 0.74 | ALK (0.51) | IGF1RMAP4K1PTK2 | |
| SCHEMBL24565257 | 0.74 | MAP4K1 (0.52) | IGF1RMAPK8MAP4K1 | |
| SCHEMBL24565264 | 0.73 | EGFR (0.56) | — | |
| SCHEMBL24565179 | 0.71 | MAP4K1 (0.57) | IGF1RMAPK8MAP4K1TTKGRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |