Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 12/20 | 0.57 |
| ▸ | IGF1R | P08069 | 5/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.51 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565324 | 0.82 | IGF1R (0.59) | MAP4K1IGF1RMAPK8TTKGRK5 | |
| SCHEMBL24565262 | 0.81 | MAP4K1 (0.57) | MAP4K1IGF1RMAPK8GRK5 | |
| SCHEMBL24565236 | 0.77 | IGF1R (0.58) | MAP4K1IGF1RMAPK8TTKGRK5 | |
| SCHEMBL24565257 | 0.74 | MAP4K1 (0.52) | MAP4K1IGF1RMAPK8ALK | |
| SCHEMBL24565244 | 0.72 | IGF1R (0.59) | MAP4K1IGF1RMAPK8TTKGRK5 | |
| SCHEMBL24565450 | 0.71 | IGF1R (0.57) | MAP4K1IGF1RMAPK8TTKGRK5 | |
| SCHEMBL2206437 | 0.70 | IGF1R (0.68) | IGF1RMAPK8ALKGRK5 | |
| SCHEMBL12430016 | 0.69 | IGF1R (0.67) | IGF1RMAPK8ALKGRK5 | |
| SCHEMBL12429331 | 0.69 | IGF1R (0.75) | MAP4K1IGF1RMAPK8ALKGRK5 | |
| SCHEMBL24565472 | 0.69 | EGFR (0.61) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |