SCHEMBL2456546

SCHEMBL2456546

O=C(O)CC(C(=O)O)c1ccccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
CYP1A2 P05177 1/20 0.57
TSHR P16473 1/20 0.57
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 2/20 0.49
KDM4E B2RXH2 2/20 0.49
USP2 O75604 1/20 0.49
POLB P06746 1/20 0.49
CTSA P10619 9/20 0.46
ACP3 P15309 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23886599 0.83 MEN1 (0.51) MEN1KMT2ACYP1A2TSHRALDH1A1
SCHEMBL30370732 0.83 MEN1 (0.51) MEN1KMT2ACYP1A2TSHRALDH1A1
SCHEMBL7812432 0.83 MEN1 (0.51) MEN1KMT2ACYP1A2TSHRALDH1A1
SCHEMBL23886595 0.83 MEN1 (0.51) MEN1KMT2ACYP1A2TSHRALDH1A1
SCHEMBL30370919 0.83 MEN1 (0.51) MEN1KMT2ACYP1A2TSHRALDH1A1
SCHEMBL21632329 0.81 MEN1 (0.50) MEN1KMT2ACYP1A2TSHRALDH1A1
SCHEMBL30821928 0.81 KCNQ2 (0.50) MEN1KMT2AALDH1A1HSD17B10ACP3
SCHEMBL23886692 0.81 MEN1 (0.50) MEN1KMT2ACYP1A2TSHRALDH1A1
SCHEMBL1489632 0.81 KCNQ2 (0.50) MEN1KMT2AALDH1A1HSD17B10ACP3
SCHEMBL11047144 0.79 AKR1B1 (0.47) MEN1KMT2ACTSAACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4323415-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2024-02-21 EP disclosed
CN-116648230-A Composition for caring skin 莱雅公司 2023-08-25 CN disclosed
EP-2542592-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.R.L. (IT) 2013-01-09 EP disclosed
WO-2011107371-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2011-09-09 WO disclosed
EP-1525231-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-04-27 EP disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed
EP-1088009-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-04-04 EP disclosed
WO-2000063261-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-26 WO disclosed