Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROS1 | P08922 | 2/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 18/20 | 0.57 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565201 | 0.95 | ROS1 (0.59) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL24565260 | 0.90 | EGFR (0.58) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL24565268 | 0.88 | ALK (0.47) | ROS1ALKEGFR | |
| SCHEMBL24565264 | 0.87 | EGFR (0.56) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL24565466 | 0.87 | ALK (0.55) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL24565245 | 0.86 | ALK (0.61) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL1707766 | 0.84 | EGFR (0.61) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL24565334 | 0.83 | EGFR (0.57) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL9911236 | 0.83 | EGFR (0.64) | ROS1ALKEGFRMETLRRK2 | |
| SCHEMBL24565166 | 0.82 | EGFR (0.55) | ROS1ALKEGFRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |