Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.61 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.56 |
| ▸ | ROS1 | P08922 | 3/20 | 0.56 |
| ▸ | INSR | P06213 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.52 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.52 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565334 | 0.86 | EGFR (0.57) | EGFRLRRK2ALKROS1INSR | |
| SCHEMBL24565245 | 0.82 | ALK (0.61) | EGFRLRRK2ALKROS1INSR | |
| SCHEMBL24565201 | 0.81 | ROS1 (0.59) | EGFRLRRK2ALKROS1 | |
| SCHEMBL1707766 | 0.81 | EGFR (0.61) | EGFRLRRK2ALKROS1 | |
| SCHEMBL24565260 | 0.81 | EGFR (0.58) | EGFRLRRK2ALKROS1INSR | |
| SCHEMBL24565264 | 0.80 | EGFR (0.56) | EGFRLRRK2ALKROS1INSR | |
| SCHEMBL9911236 | 0.80 | EGFR (0.64) | EGFRLRRK2ALKROS1INSR | |
| Hydrochloric Acid SCHEMBL1707842 | 0.79 | EGFR (0.63) | EGFRLRRK2ALKROS1INSR | |
| SCHEMBL24565479 | 0.78 | ROS1 (0.59) | EGFRLRRK2ALKROS1 | |
| SCHEMBL1460537 | 0.77 | EGFR (1.00) | EGFRLRRK2ALKINSRGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |