Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565459 | 0.88 | PTK2 (0.46) | BRD4PTK2EGFRAAK1ALK | |
| SCHEMBL24565296 | 0.87 | ALK (0.44) | BRD4PTK2AAK1ALK | |
| SCHEMBL24565259 | 0.79 | AAK1 (0.39) | EGFRAAK1 | |
| SCHEMBL24565192 | 0.78 | WEE1 (0.42) | BRD4PTK2EGFRALKJAK2 | |
| SCHEMBL29747126 | 0.74 | PTK2 (0.50) | PTK2EGFRALKJAK2 | |
| SCHEMBL29746907 | 0.74 | PTK2 (0.53) | PTK2EGFRALK | |
| SCHEMBL24565202 | 0.74 | MAPK9 (0.47) | BRD4PTK2EGFRALK | |
| SCHEMBL24565470 | 0.73 | PTK2 (0.49) | PTK2 | |
| SCHEMBL24565159 | 0.72 | EGFR (0.41) | EGFR | |
| SCHEMBL24565279 | 0.72 | EGFR (0.59) | BRD4PTK2EGFRALKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |