Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 4/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCND3 | P30281 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.43 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22460248 | 0.83 | EGFR (0.60) | EGFRALKPTK2INSRIGF1R | |
| SCHEMBL22460093 | 0.83 | EGFR (0.60) | EGFRALKPTK2INSRIGF1R | |
| SCHEMBL29747072 | 0.83 | EGFR (0.56) | MAPK9MAPK10CCNKCCNA2CDK2 | |
| SCHEMBL24429801 | 0.83 | EGFR (0.60) | EGFRALKPTK2INSRIGF1R | |
| SCHEMBL29746768 | 0.83 | ZAP70 (0.56) | MAPK9MAPK10MAPK8CCNKCCNA2 | |
| SCHEMBL29747119 | 0.83 | ZAP70 (0.56) | MAPK9MAPK10MAPK8CCNKCCNA2 | |
| SCHEMBL29747821 | 0.83 | EGFR (0.56) | MAPK9MAPK10CCNKCCNA2CDK2 | |
| SCHEMBL24565459 | 0.74 | PTK2 (0.46) | MAPK8EGFRALKPTK2IGF1R | |
| SCHEMBL24565476 | 0.74 | BRD4 (0.40) | EGFRALKPTK2BRD4 | |
| SCHEMBL22460299 | 0.72 | EGFR (0.56) | EGFRALKPTK2INSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |