Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384635 | 0.81 | CYP1A2 (0.56) | CYP1A2HIF1ACYP2C19TSHRALDH1A1 | |
| SCHEMBL3433832 | 0.79 | CYP1A2 (0.54) | CYP1A2HIF1ACYP2C19TSHRALDH1A1 | |
| SCHEMBL15125011 | 0.79 | CYP1A2 (0.54) | CYP1A2HIF1ACYP2C19TSHRALDH1A1 | |
| SCHEMBL15228092 | 0.79 | CYP1A2 (0.54) | CYP1A2HIF1ACYP2C19TSHRALDH1A1 | |
| SCHEMBL6548609 | 0.78 | HIF1A (0.57) | CYP1A2HIF1ACYP2C19MIFTSHR | |
| SCHEMBL28689277 | 0.78 | CYP1A2 (0.52) | CYP1A2HIF1ACYP2C19TSHRALDH1A1 | |
| SCHEMBL11637439 | 0.77 | TDP1 (0.44) | CYP1A2CYP2C19TSHRALDH1A1MAPT | |
| SCHEMBL15125012 | 0.77 | HIF1A (0.55) | CYP1A2HIF1ACYP2C19MIFTSHR | |
| SCHEMBL5925077 | 0.76 | CYP1A2 (0.50) | CYP1A2HIF1ACYP2C19TSHRALDH1A1 | |
| SCHEMBL27466589 | 0.76 | CYP1A2 (0.50) | CYP1A2HIF1ACYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101289387-A | 6-chlor-2,3-dihydro- indene-3-ketone-1-carboxyl acid optical isomer and method for preparing same | UNIV CHINA PHARMA (CN) | 2008-10-22 | — | — | CN | claimed |
| EP-4323415-A1 | PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2024-02-21 | — | — | EP | disclosed |
| CN-116648230-A | Composition for caring skin | 莱雅公司 | 2023-08-25 | — | — | CN | disclosed |
| EP-2542592-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.R.L. (IT) | 2013-01-09 | — | — | EP | disclosed |
| CN-102040556-B | Optical isomer of indene quinolone, preparation method and medical application thereof | YANGTZE RIVER PHARM GROUP CO | 2012-05-23 | — | — | CN | disclosed |
| WO-2011107371-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2011-09-09 | — | — | WO | disclosed |
| CN-102040556-A | Optical isomers of indene quinazoline, preparation method and medicinal application thereof | YANGTZE RIVER PHARM GROUP CO | 2011-05-04 | — | — | CN | disclosed |
| CN-101289387-A | 6-chlor-2,3-dihydro- indene-3-ketone-1-carboxyl acid optical isomer and method for preparing same | UNIV CHINA PHARMA (CN) | 2008-10-22 | — | — | CN | disclosed |
| EP-1525231-A1 | CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.P.A. (IT) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004005359-A1 | CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-01-15 | — | — | WO | disclosed |
| EP-1088009-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Technology Company B.V. (NL) | 2001-04-04 | — | — | EP | disclosed |
| WO-2000063261-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2000-10-26 | — | — | WO | disclosed |